浙江省奉化市18岁及以上人群血脂水平及其影响因素调查

目的 了解浙江省奉化市18岁及以上人群血脂水平及其影响因素,为心血管疾病预防提供依据。 方法 采用多阶段分层整群随机抽样方法调查奉化市18岁以上人群600人,采取问卷调查、体格检查和生化检测的方法,进行血脂水平及其影响因素的调查。计量资料用x s表示,组间比较用t检验,计数资料和率的比较用Pearson 2检验和趋势2检验,多因素分析采用非条件logistic回归分析方法。 结果 调查对象血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)平均水平分别为3.95 mmol/L、1.36 mmol/L、2.25 mmol/L和1.02 mmol/L。女性TC、LDL-C和HDL-C平均水平高于男性,差异有统计学意义(TC: t=-3.216,P=0.001;LDL-C: t=-2.396,P=0.017;HDL-C:t=2.498,P=0.013),男女间TG平均水平差异无统计学意义(t=-1.451,P=0.147)。血脂异常率为64.50%,标化异常率为45.47%,血脂边缘异常率为6.33%,标化边缘异常率为4.19%,血脂异常率随年龄增长而增加(趋势2=13.884,P=0.000)。TC、TG、LDL-C和HDL-C标化异常率分别为1.53%、6.78%、1.04%和42.92%,其中 HDL-C异常率男女间差异有统计学意义(2=7.181,P=0.007),且具有增龄趋势(趋势2=10.371,P=0.001)。logistic多因素分析显示,中心性肥胖、年龄、超重或肥胖是血脂异常的危险因素。 结论 奉化市18岁及以上人群血脂异常患病率较高,特别是HDL-C异常患病率较高。应针对血脂异常的危险因素开展社区血脂异常综合防治工作。

Plasma lipids level and related factors in adults in Fenghua, Zhejiang

Objective To learn about the plasma lipids level and related factors among the residents aged ≥18 years in Fenghua. Methods Multistage random cluster sampling were conducted to select study subjects, questionnaire survey, health examination and biochemical detection were performed among the selected subjects. The data were analyzed by t-test, χ2 test and χ2trend test. The risk factors of dyslipidemia were analyzed by non-conditional logistic regression analysis. Results Totally 600 people aged ≥ 18 years were surveyed. The average levels of TC, TG, LDL-C and HDL-C were 3.95, 1.36, 2. 25 and 1.02 mmol/L, respectively. The TC, LDL-C and HDL-C levels in females were higher than those in the males （ TC： t = - 3. 216, P = 0. 001 ; LDL-C： t = - 2. 396, P = 0. 017 ; HDL-C： t = 2. 498, P =0. 013）, the difference had statistical significance. The difference in TG levels between males and females had no statistical significance （t = - 1. 451, P = 0. 147 ）. The dyslipidemia rate and borderline dyslipidemia rate were 64. 50% and 6. 33%, respectively. The age-adjusted standardized dyslipidemia rate and borderline dyslipidemia rate were 45.47% and 4. 19% , respectively. The prevalence of dyslipidemia increased withage （χ2trends = 13. 884 , P = 0. 000）. The age-adjusted standardized abnormal rates of TC, TG, LDL-C and HDL-C were 1.53%, 6. 78%, 1.04% and 42. 92% respectively. The abnormal rate of HDL-C was higher in males than that in females （χ2 = 7. 181, P = 0. 007 ）and increased with age. The risk factors of dyslipidemia included central obesity, aging and overweight or obesity. Conclusion High prevalence of dyslipidemia was found among the residents aged ≥ 18 years old in Fenghua, especially the high abnormal rate of HDL-C. It is necessary to conduct targeted community based dyslipidemia prevention and treatment.