我院694例药品不良反应报告分析 |
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引用本文: | 谢洪先,邓秀碧,王良玉,罗 静,陈宇宁. 我院694例药品不良反应报告分析[J]. 中国药房, 2014, 0(22): 2072-2074 |
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作者姓名: | 谢洪先 邓秀碧 王良玉 罗 静 陈宇宁 |
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作者单位: | [1]重庆市璧山县人民医院药剂科,重庆402760; [2]成都市新都区人民医院,成都610500 |
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摘 要: | 目的:了解我院药品不良反应(ADR)发生的特点,促进临床合理用药。方法:对我院2008-2013年收集的694例ADR报告按患者的年龄、性别、给药途径、用药情况及ADR临床表现等进行回顾性分析。结果:694例ADR报告中,给药途径以静脉给药为主,占73.34%;药品种类中抗感染药引发ADR例数最多(占57.35%),其次为中药制剂(占19.31%);ADR损害器官或系统以皮肤及其附件为主(占45.10%),其次为神经系统和消化系统(分别占25.36%和19.02%)。结论:临床应提高ADR监测报告质量,加强抗感染药的合理使用,减少ADR的发生,保障公众用药安全。
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关 键 词: | 药品不良反应 监测 合理用药 |
Analysis of 694 Cases of ADR Reports in Our Hospital |
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Affiliation: | XIE Hong-xian, DENG Xiu-bi, WANG Liang-yu, LUO Jing, CHEN Yu-ning ( 1. Dept. of Pharmacy, Chongqing Bishan County People's Hospital, Chongqing 402760, China; 2. Chengdu Xindu District People's Hospi- tal, Chengdu 610500, China) |
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Abstract: | OBJECTIVE: To investigate the characteristics of ADR in our hospital, and to promote rational drug use. METH- ODS: A total of 694 ADR reports in our hospital during 2008- 2013 were analyzed statistically in respects of age and gender, route of administration, drug categories and clinical manifestations, etc. RESULTS: Among 694 cases, intravenous administration took the lead among the routes of administration (73.34%); 57.35% were induced by anti-infective drugs, showing the biggest pro- portion, followed by TCM preparations (19.31%); ADR dominantly manifested as lesions of skin and its appendants (45.10%), followed by injury of nervous system and digestive system (25.36% and 19.02 % ). CONCLUSIONS: Great importance must be attached to the quality of ADR monitoring and use of anti-infective drugs should be strengthened in order to reduce the occurrence of ADR and guarantee the safety of drug use in the public. |
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Keywords: | ADR Monitoring Rational drug use |
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