微量喂养联合益生菌思连康预防早产儿坏死性小肠结肠炎发生的有效性分析

目的对比不同喂养方法对早产儿坏死性小肠结肠炎（NEC）的预防作用。方法将我院收治的128例早产儿依据喂养方式差异随机分为两组,其中65例采用早期微量喂养结合益生菌思连康喂养设为观察组,其余63例仅采用早期微量喂养设为对照组,对比两组NEC的预防效果。结果观察组以3.08%的NEC发生率远不及对照组14.09%高（P〈0.05）;两组出生后第1天胃泌素与胃动素水平差异无统计学意义（P〉0.05）;出生7 d与14 d后此两项水平差异显著（P〈0.05）;组间感染、贫血、呼吸暂停的发生率差异无统计学意义（P〉0.05）,但对照组并发高胆红素血症的例数明显高于观察组（P〈0.05）。结论给予早产儿微量喂养联合益生菌思连康喂养可有效预防其NEC的发病,该法值得临床采纳。

The validity analysis of minimal feeding combined with probiotics siliankang in preventing necrotizing enterocolitis of preterm infant

【Objective】 To compare preventive effect of different feeding method for necrotizing enterocolitis（NEC） of premature babies. 【Methods】128 cases of premature infants in our hospital were randomly divided into two groups based on differences in feeding. 65 cases with early minimal feeding combined with probiotics siliankang were set as observation group, and the rest of the 63 cases with early minimal feeding were set as control group. Prevention effect of NEC in the two groups were compared. 【Results】3.08% of the incidence of NEC in observation group was far less than 14.09% of the control group（P〈0.05）; Stomach and moving element level differences in the two groups after first birth day had no statistical significance（P〉0.05）; The two levels at 7 days and 14 days after the birth differed significantly（P〈0.05）; There was no statistically significant difference between the incidence of infection, anemia and apnea in the two groups（P〉0.05）, but the concurrent cases of high blood bilirubin in the controls were obviously higher than that of observation group（P〈0.05）. 【Conclusion】Giving premature minimal feeding combined with probiotics siliankang is effective in preventing the onset of the NEC, which is worth clinical adoption.