针刺治疗偏头痛的疗效及生化学机制研究

目的　明确针刺治疗偏头痛的临床疗效 ,探讨针刺治疗偏头痛的生化学机制。方法　将 63例偏头痛患者随机分为针刺组和对照组 ,观察临床疗效及治疗前后血中 PAF、TXB2 、6-酮 - PGF1 a含量 ,并选择 2 0名健康人作为正常对照组。结果　针刺治疗偏头痛 ,总有效率达 90 .6% ,优于对照组 ( P<0 .0 1) ;偏头痛患者 PAF、TXB2 、6-酮 - PGF1 a含量经针刺治疗后有改善 ( P<0 .0 1)。结论　针刺治疗偏头痛疗效明显 ;针刺对偏头痛患者血中 PAF、TXB2 、6-酮 - PGF1 a有调节作用

Research into the Clinical Curative Effect of Acupuncture on Migraine and Its Biochemical Mechanism

Purpose To prove the clinical curative effect of acupuncture on migraine and investigate its biochemical mechanism. Method Sixty three migraine patients were randomly divided into an acupuncture group and a control group. The clinical curative effect, and blood PAF, TXB 2 and 6 keto PGF 1a contents before and after treatment were observed. Twenty healthy persons were selected as a normal control group. Results The total effective rate from acupuncture treatment of migraine reached 90.6%, which was higher than that in the control group ( P <0.01). PAF, TXB 2 and 6 keto PGF 1a contents decreased in migraine patients after acupuncture. Conclusion Acupuncture has a marked curative effect on migraine. PAF, TXB 2 and 6 keto PGF 1a are all involved in the pathologic process of migraine. Acupuncture has a regulative effect on blood PAF, TXB 2 and 6 keto PGF 1a in migraine patients.