| 基因探针监测巨细胞病毒潜伏感染的母儿间传播 |
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| 引用本文： | 谭季春,周吉海,乐杰.基因探针监测巨细胞病毒潜伏感染的母儿间传播[J].中国优生与遗传杂志,1995,3(4):10-11,32. |
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| 作者姓名： | 谭季春 周吉海 乐杰 |
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| 作者单位： | [1]沈阳市妇婴医院，110014 [2]白求恩医科大学一院妇产科 |
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| 摘 要： | 本文采用基因探针检测孕妇静脉血及新生儿脐静脉血白细胞中CMVDNA，同时应用ELISA检测其血清中IgG、IgM．结果：10例孕妇CMV-DNA阳性，占8．7％(10／115)，这10例孕妇血IgG均阳性，IgM均阴性；17例新生儿CMV—DNA阳性．占14．3％(17／119)，其中IgM阳性2例，占1．7％(2／119)。本次研究中配对者79例，母儿CMV—DNA均阳性者8例，新生儿CMV—DNA阳性而母亲阴性者4例。上述CMV-DNA阳性者均无临床症状。研究结果提示基因探针可监测CMV的潜伏感染，从而进一步研究CMV感染的母儿传播机制。
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| 关 键 词： | 阳性 CMV 母儿 潜伏感染 基因探针 新生儿 DNA 配对 |
Surveyed CMV lacent infection in pregnancies and their infants by hybridization |
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| Tan Ji-chun et al..Surveyed CMV lacent infection in pregnancies and their infants by hybridization[J].Chinese Journal of Birth Health & Heredity,1995,3(4):10-11,32. |
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| Authors: | Tan Ji-chun |
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| Abstract: | Cytomegalovirus(CMV) DNA were detected in white blood cells from pregnancies and their infants by hybridization. Result 10 of the 115 pregnancies were positive(8.7%).17 of the 119 infants were positive(14.3%).In this study, matched 79cases, there were 8 cases positive both pregnancies and their infants.4 cases infants positive,while their mothers were negtive.All the objects in the study were no significant clinical manifestation.This report showed hybridization may survey CMV lacent infection in pregnancies and their infants. |
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| Keywords: | Gene probe Latent infecTion Pregnant woman Newborn baby |
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