Coronary artery bypass in hereditary factor XI deficiency |
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Authors: | R Brunken D Follette J Wittig |
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Institution: | Cardiology Division of the Department of Medicine and the Thoracic Surgery Division of the Department of Surgery, University of California, Los Angeles, Center for the Health Sciences, Los Angeles, CA |
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Abstract: | Hereditary factor XI deficiency is a disorder of coagulation that has been associated with postoperative bleeding. Because cardiopulmonary bypass itself induces transient abnormalities in hemostasis, the patient with factor XI deficiency could be at increased risk for bleeding after cardiac surgical procedures. We report the successful management of a 61-year-old man with hereditary factor XI deficiency who had coronary artery bypass. Treatment with low-dose aspirin, begun 24 hours postoperatively for graft patency, was well tolerated. Once recognized and aggressively treated, factor XI deficiency does not appear to be a contraindication to potentially life-saving procedures like coronary revascularization. |
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Keywords: | Address reprint requests to Dr Wittig Division of Thoracic Surgery Department of Surgery UCLA Center for the Health Sciences 10833 Le Conte Ave Los Angeles CA 90024 |
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