Adhesion formation is reduced after laparoscopic surgery |
| |
Authors: | C. L. Garrard R. H. Clements L. Nanney J. M. Davidson W. O. Richards |
| |
Affiliation: | (1) Department of Surgery, MCN-D5203 Vanderbilt University Medical Center, Nashville, TN 37232, USA, US;(2) Department of Plastic Surgery, MCN-D5203 Vanderbilt University Medical Center, Nashville, TN 37232, USA, US;(3) Department of Cell Biology, MCN-D5203 Vanderbilt University Medical Center, Nashville, TN 37232, USA, US;(4) Department of Pathology, MCN-D5203 Vanderbilt University Medical Center, Nashville, TN 37232, USA, US;(5) Department of Veterans Affairs Medical Center, MCN-D5203 Vanderbilt University Medical Center, Nashville, TN 37232, USA, US |
| |
Abstract: | Background: Adhesion formation after abdominal operations causes significant morbidity. Methods: Adhesion formation in pigs was compared after placement of prosthetic mesh during celiotomy (group 1), laparoscopy with large incision (group 2), and laparoscopy (group 3). After peritoneum was excised, polypropylene mesh was fixed to the abdominal wall, then to the opposite abdominal wall in the preperitoneal space followed by peritoneal closure. Adhesion area, grade, and vascularity were measured. Results: More adhesions (p < 0.02) covered intraperitoneal mesh (7.57 ± 1.89 cm2) than covered reperitonealized mesh (2.16 ± 1.13 cm2), and adhesion grade was significantly greater (p < 0.02). Adhesion areas were significantly greater in groups 1 and 2 than in group 3 (p= 0.001 and 0.03, respectively). Adhesion grade was significantly greater in groups 1 and 2 than in group 3 (p= 0.02 and p= 0.04, respectively). Groups 1 and 2 had more vascular adhesions than group 3 (p < 0.01 and p= 0.02, respectively) Conclusions: A foreign body within the peritoneum stimulates more numerous and denser adhesions. Tissue trauma distant from the site of adhesions increases their formation. A major advantage of laparoscopic surgery is decreased adhesion formation. Received: 23 January 1998/Accepted: 10 March 1998 |
| |
Keywords: | : Adhesions (formation, grade, vascularity) — Laparoscopy — Tissue trauma |
本文献已被 SpringerLink 等数据库收录! |
|