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局部三联疗法治疗黄褐斑临床疗效观察
引用本文:匡薇薇,张瑞丽,任虹.局部三联疗法治疗黄褐斑临床疗效观察[J].职业与健康,2010,26(10):1189-1190.
作者姓名:匡薇薇  张瑞丽  任虹
作者单位:江苏省连云港市第一人民医院,222000
摘    要:目的观察局部三联疗法(2%氢醌乳膏、0.1%全反式维A酸乳膏、0.1%丁酸氢化可的松软膏)治疗黄褐斑的临床疗效及安全性。方法采用随机、双盲、对照方法。将120例黄褐斑患者随机分为3组,A组40例,采用2%氢醌乳膏、0.1%全反式维A酸乳膏联合0.1%丁酸氢化可的松软膏治疗;B组40例,单用2%氢醌乳膏治疗;C组40例,单用0.1%全反式维A酸乳膏治疗。各组均连续治疗12周并判断疗效及不良反应。结果A组治疗黄褐斑疗效优于B组、C组,疗效差别有统计学意义(P0.05),且不良反应少。结论局部三联疗法治疗黄褐斑疗效好,安全性高,是治疗黄褐斑的理想方法之一。

关 键 词:三联疗法  黄褐斑

Observation of Clinical Effect of Local Triple Therapy in the Treatment of Chloasma
KUANG Wei-wei,ZHANG Rui-li,REN Hong.Observation of Clinical Effect of Local Triple Therapy in the Treatment of Chloasma[J].Occupation and Health,2010,26(10):1189-1190.
Authors:KUANG Wei-wei  ZHANG Rui-li  REN Hong
Institution:KUANG Wei-wei,ZHANG Rui-li,REN Hong (Department of Dermatology,the First People\'s Hospital of Lianyungang,Jiangsu,222000,China)
Abstract:Objective]To observe the clinical efficacy and safety of the triple therapy (2% hydroquinone cream,0.1% all-trans retinoic acid cream and 0.1% hydrocortisone butyrate ointment) in the treatment of chloasma.Methods]A randomized,double-blind and controlled method was adopted.120 patients with chloasma were randomly divided into three groups.Group A (40 cases) was treated with the combination of 2% hydroquinone cream,0.1% all-trans retinoic acid cream and 0.1% hydrocortisone butyrate ointment,group B (40 cas...
Keywords:Triple therapy  Chloasma  
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