Institution: | a Medical Biomechanical Laboratory of PLA, The First Military Medical University, Guangzhou, P.R. China b Institute of Applied Mechanics, Taiyuan University of Technology, Taiyuan, P.R. China |
Abstract: | Objective. To evaluate the effect of strain rate (?3), apparent density (a) and tissue density (t) on Young's modulus (E), strength (σu) and ultimate strain (u) on intervertebral bone from a Chinese population. Methods. Testing was performed by uniaxial compression at five strain rates on 36 human trabecular bone specimens from three male T12?L4 vertebrae. Results. Apparent density ranged between 0.46 and 0.71 g/cm3. Tissue density ranged between 1.02 and 1.54 g/cm3. Non-linear regression analyses using strength, Young's modulus or ultimate strain as dependent variables (Y) and strain rate and apparent density or tissue density as independent variables were performed using the following equation: Y = ab?3c. The exponent of apparent density and strain rate to Young's modulus were 1.88 and 0.07, separately (P = 0.0007). The variation of strength was explained only by apparent density with an exponent of 1.29 (P = 0.0107). The variation of Young's modulus was explained equally by the quadratic and cubic relationship to apparent density or tissue density (P < 0.01). Ultimate strain varied independently of apparent density or tissue density and strain rate. |