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Refractory oedema: think about systemic capillary leak syndrome |
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| Authors: | Chiche L Donati S Granier I Arnal J-M Durand-Gasselin J |
| Institution: | 1. Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, Berlin, Germany;2. Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel |
| Abstract: | Systemic Capillary Leak Syndrome (SCLS) is a rare and recently discovered disease. The diagnosis must be evoked in front of an hypovolaemic shock associated with a refractory anasarca. We report an observation of SCLS and then discuss the diagnostic and therapeutic difficulties. SCLS is diagnosed when a patient meet a compatible clinical situation with an hypoalbuminemia in spite of relative hemoconcentration. Evidence of a monoclonal gammapathy constitute an additional clue. |
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