The relationships between blood lead levels and serum follicle stimulating hormone and luteinizing hormone in the National Health and Nutrition Examination Survey 1999-2002 |
| |
Authors: | Krieg Edward F Feng Huiling A |
| |
Affiliation: | a National Institute for Occupational Safety and Health, Robert A. Taft Laboratories, 4676 Columbia Parkway, MS C-22, Cincinnati, OH 45226, United States b National Institute for Occupational Safety and Health, Alice B. Hamilton Laboratories, 5555 Ridge Road, MS R-3, Cincinnati, OH 45213, United States |
| |
Abstract: | The relationships between blood lead levels and serum follicle stimulating hormone and luteinizing hormone were assessed in a nationally representative sample of women, 35-60 years old, from the National Health and Nutrition Examination Survey 1999-2002. The blood lead levels of the women ranged from 0.2 to 17.0 μg/dL. The estimated geometric mean was 1.4 μg/dL, and the estimated arithmetic mean was 1.6 μg/dL. As the blood lead level increased, the concentration of serum follicle stimulating hormone increased in post-menopausal women, women who had both ovaries removed, and pre-menopausal women. The concentration of luteinizing hormone increased as blood lead level increased in post-menopausal women and women who had both ovaries removed. The lowest concentrations of blood lead at which a relationship was detected were 0.9 μg/dL for follicle stimulating hormone and 3.2 μg/dL for luteinizing hormone. Lead may act directly or indirectly at ovarian and non-ovarian sites to increase the concentrations of follicle stimulating hormone and luteinizing hormone. |
| |
Keywords: | NHANES Blood lead Follicle stimulating hormone Luteinizing hormone FSH LH |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|