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非小细胞肺癌脑转移80例预后分析
引用本文:邓明佳,冯志平,沈丽达. 非小细胞肺癌脑转移80例预后分析[J]. 肿瘤基础与临床, 2011, 24(5): 424-425
作者姓名:邓明佳  冯志平  沈丽达
作者单位:云南省肿瘤医院肿瘤化疗研究中心,云南昆明,650118
摘    要:目的 探讨非小细胞肺癌脑转移患者的预后相关因素.方法对80例非小细胞肺癌脑转移患者的临床资料进行回顾性分析.结果非小细胞肺癌脑转移患者原发肿瘤控制与否,颅内转移灶<3个或≥3个者,KPS≥70分或<70分者,有无神经功能障碍者及治疗与否等的生存期两两比较差异均有统计学意义(P<0.05).年龄≥65岁或<65岁,有或无...

关 键 词:非小细胞肺癌  脑转移  预后因素

The Prognosis Analysis of Brain Metastases of Non-Small Cell Lung Cancer: Review of 80 Cases
Deng Mingjia,Feng Zhiping,ShenLida. The Prognosis Analysis of Brain Metastases of Non-Small Cell Lung Cancer: Review of 80 Cases[J]. journal of basic and clinical oncology, 2011, 24(5): 424-425
Authors:Deng Mingjia  Feng Zhiping  ShenLida
Affiliation:(Center of Cancer Chemotherapy,Yunnan Province Tumor Hospital,Kunming 650118,China)
Abstract:Objective To investigate the prognostic factors of brain metastases of non-small cell lung cancer.Methods The clinical data of 80 patients with brain metastases of non-small cell lung cancer were analyzed retrospectively.Results There was significant difference between the survival time of the patients with primary tumor controlled or not,KPS≥70 or <70,the number of the brain metastases was ≥3 or <3,had nerval function abnormity or not,and the patients received treatment or not(P<0.05).There was no significant difference between the patients with outside brain metastases or not and ≥65 years or <65 years(P>0.05).Correlation analysis showed: the survival time of the patients had correlation with KPS,primary tumor controlled or not,the number of brain metastasis tumor and the patients received treatment or not(r=0.624,0.656,0.577,0.524;P<0.05).Conclusion The prognosis of the patients with brain metastases of non-small cell lung cancer is in relation to KPS,primary tumor controlled or not,the number of the brain metastases and the patients received treatment or not.
Keywords:non-small cell lung cancer  brain metastases  prognostic factors
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