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人乳头瘤病毒感染与梅州地区非小细胞肺癌发生的关系
引用本文:张锦丰,郑中文,王苏美,杨权烈,李亮,邓国明.人乳头瘤病毒感染与梅州地区非小细胞肺癌发生的关系[J].肿瘤基础与临床,2011,24(5):377-379.
作者姓名:张锦丰  郑中文  王苏美  杨权烈  李亮  邓国明
作者单位:1. 梅州市人民医院化疗科,广东梅州,514031
2. 中山大学中山医学院病理生理学教研室,广东广州,510080
3. 梅州市人民医院肿瘤外科,广东梅州,514031
摘    要:目的 探讨人乳头瘤病毒( HPV)感染与梅州地区非小细胞肺癌(NSCLC)发生的关系.方法应用免疫组织化学SABC法检测43例NSCLC和27例肺良性病变组织中HPV的表达情况.结果HPV在NSCLC和肺良性病变组织中的检出率分别为39.5%和7.4%,差异有统计学意义(P=0.003).结论HPV感染与梅州地区NSC...

关 键 词:人乳头瘤病毒  非小细胞肺癌  免疫组织化学

The Relationship Between Human Papillomavirus Infection and Non-Small Cell Lung Cancer in Meizhou
Zhang Jinfeng,Zheng Zhongwen,Wang Sumei,Yang Quanlie,Li Liang,Deng Guoming.The Relationship Between Human Papillomavirus Infection and Non-Small Cell Lung Cancer in Meizhou[J].journal of basic and clinical oncology,2011,24(5):377-379.
Authors:Zhang Jinfeng  Zheng Zhongwen  Wang Sumei  Yang Quanlie  Li Liang  Deng Guoming
Institution:1.Department of Chemotherapy,Meizhou People’s Hospital,Meizhou 514031,China;2.Department of Pathophysiology,Zhongshan School of Medicine,Sun Yat-Sen University,Guangzhou 510080,China;3.Department of Surgical Oncology,Meizhou People’s Hospital,Meizhou 514031,China)
Abstract:Objective To investigate the relationship between human papillomavirus(HPV) infection and the pathogenesis of non-small cell lung cancer(NSCLC) in Meizhou.Methods Immunohistochemical SABC method was used to detect the expression of HPV in 43 cases of NSCLC and 27 cases of lung benign diseases.Results The positive rate in the NSCLC was 39.5%,and was 7.4% in the lung benign diseases(P=0.003).Conclusion HPV infection may play an important role in the pathogenesis of NSCLC in Meizhou.
Keywords:human papillomavirus  non-small cell lung cancer  immunohistochemisty
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