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GnRH-a治疗腹腔镜术后子宫内膜异位症合并不孕症的作用机制与疗效
引用本文:陈建欢,马彩玲.GnRH-a治疗腹腔镜术后子宫内膜异位症合并不孕症的作用机制与疗效[J].生殖与避孕,2013,33(5):333-337.
作者姓名:陈建欢  马彩玲
作者单位:新疆医科大学第一附属医院妇科,乌鲁木齐,830054
基金项目:自治区自然科学基金面上项目
摘    要:子宫内膜异位症(EMs)是育龄期女性的常见病,其中高达40%的患者合并不孕症。促性腺激素释放激素激动剂(GnRH-a)联合腹腔镜手术已成为治疗EMs相关不孕症的重要治疗措施,其通过改善盆腹腔微环境、提高子宫内膜容受性、提高卵泡及胚胎质量等多方面改善EMs患者的生育能力,对提高腹腔镜术后EMs患者的自然妊娠与辅助妊娠结局具有一定的价值。

关 键 词:促性腺激素释放激素激动剂(GnRH-a)  子宫内膜异位症(EMs)  不孕症  腹腔镜

Mechanism of Action of GnRH Agonist Treatment for Endometriosis-associated Infertility after Laparoscopic Surgery and Its Efficacy
Abstract:Endometriosis(EMs) is a common disease for women of reproductive age,up to 40% of patients got infertility.Gonadotropin-releasing hormone agonist(GnRH-a) combined with laparoscopic surgery has become an important therapeutic measure for EMs-associated infertility,by improving the abdominal and pelvic microenvironment,the receptivity of endometrium to embryo and increasing the quality of follicle as well as embryo to enhance the fertility of patients with EMs.The value of GnRH-a treatment in combination with laparoscopic surgery and assisted reproductive technique(ART) to improve the pregnancy outcome of EMs is significant to extent.
Keywords:GnRH agonist (GnRH-a)  endometriosis (EMs)  infertility  laparoscope
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