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Reproducibility of left ventricular area and volume measurements using a computer endocardial edge-detection algorithm in normal subjects
Authors:D A Conetta  E A Geiser  L H Oliver  A B Miller  C R Conti
Affiliation:1. School of Management, Jiangsu University, Zhenjiang, 212013, China;2. School of Business Administration, Dongbei University of Finance and Economics, Dalian, China;3. Dean at International Business College, Dongbei University of Finance and Economics, Dalian, China;1. Service de soins de suite et réhabilitation respiratoire (Département "R3S"), Groupe Hospitalier Pitié-Salpêtrière-Charles-Foix, AP-HP, 47-83 boulevard de l''Hôpital, 75013 Paris, France;2. Département de pneumologie, CHRU de Nancy, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France;3. Respiratory Support, Chronic Care Group (GAVO2) of the French respiratory Society of Respiratory Disease (SPLF), France;4. Département de Santé Publique, Groupe Hospitalier Pitié-Salpêtrière-Charles-Foix, AP-HP, 47-83 boulevard de l''Hôpital, 75013 Paris, France;5. INSERM, UMRS 1136, Institut Pierre Louis d’Épidémiologie et de Santé Publique, équipe 6, Sorbonne Université, UPMC Université Paris 06, 47-83 boulevard de l''Hôpital, 75061 Paris Cedex 13, France;6. Service de Pneumologie et Soins Intensifs Respiratoires, Centre Hospitalier Universitaire de Bourgogne, Dijon, France.;7. INSERM, UMRS 1158, Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Universités, UPMC Université Paris 06, 47-83 boulevard de l''Hôpital, 75651 Paris Cedex 13, France
Abstract:The variability of serially recorded 2-dimensional echocardiograms in normal subjects was determined. During a 2-week period, 10 normal subjects underwent echocardiography 5 times, in 2 laboratories, with use of different ultrasonographs. The video recordings were analyzed using a computer image analysis system (Quantic 1200) to provide standardized left ventricular short-axis areas and area ejection fraction (EF). Left ventricular volumes and volume EF were calculated. The 95% confidence limits of the percent difference for end-diastolic area and volume between 2 samples in a given subject were +/- 16.8 and +/- 16.7%, respectively. The limits for end-systolic area and volume were +/- 15.8 and +/- 17.0%, respectively. The 95% confidence limits for differences of area and volume EF between 2 recordings were +/- 12.8 and +/- 9.7%, respectively. No correlation was found between clinical grade (image quality) and the variability of area measurements. A good correlation (r = 0.98) was found between area and volume EF for any given subject over the 5 observations. These confidence limits are narrower than those previously recorded.
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