Lupus anticoagulant and thrombosis following Henoch-Schonlein purpura |
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Authors: | Abend Nicholas S Licht Daniel J Spencer Charles H |
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Affiliation: | Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. abend@email.chop.edu |
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Abstract: | A male adolescent developed a sinovenous thrombosis 4 weeks following a Henoch-Schonlein purpura episode. A hypercoagulation evaluation revealed a positive lupus anticoagulant. This suggests an association between Henoch-Schonlein purpura and antiphospholipid antibody syndrome and is the first report of sinovenous thrombosis after Henoch-Schonlein purpura that was likely due to elevated antiphospholipids. Children who develop Henoch-Schonlein purpura with neurologic features including headache should be evaluated for sinovenous thrombosis and a hypercoagulable state. |
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