硒与大骨节病的动态研究

大骨节病病情的自然动态变化,直接关系到病因的研究和对防治效果的判断。大骨节病X线上的影象变化能够自然修复和自愈,并有年度变化。为了通过动态的病情周测探讨其演变规律,和为评价各种药物疗效提供确切依据,我们于1982年5月至1987年5月对陕西省大骨节病区内的9个周测点进行了观察,现就六年结果分析如下:

A Study on the Trend of Selenium and Kaschin-Beck Disease

The trend of Kaschin-Beck disease in 3 types of endemic areas was studied in a 6-year surveillance. Results showed that the total prevalence rate appeared to be stable and slightly decline. The x-ray detecting rate of this disease decreased from 50.48% in 1982 to 33.07% in 1987, especially in the Loess Plateau. However, the disease in some areas were still serious. Case survey before and after the surveillance indicated that the patients' bony lesions had been improved and most of them could be spontaneously cured. Selenium contents in children's hair tended to increase, but those in grain and water remained almost the same. Mean while, there was no statistical relationship between the x-ray detecting rate of this disease and selenium in most of the investigated areas. Based on the results of the study, the authors consider that Kaschin-Beck disease in the investigated areas was stable and mild, also, the hypothesis that hyposelenium was the cause of Kaschin-Beck disease was quetionable.