Fulminant ulcerative colitis |
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Authors: | Clarence K. W. Wong MD FRCPC B. R. Yacyshyn MD FRCPC |
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Affiliation: | (1) 2E3.11, Walter MacKenzie Health Sciences Centre, 8440 112th St., T6G 2B7 Edmonton, Alberta, Canada;(2) Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada |
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Abstract: | Opinion statement – | Fulminant ulcerative colitis necessitates immediate hospitalization. | – | Supportive therapy such as aggressive rehydration, restriction of oral intake, and consideration of parenteral nutrition should be initiated. | – | High-dose intravenous steroids should be started in almost all cases. | – | Antibiotics and cyclosporine should be considered, especially in disease refractory to steroid therapy. | – | Indications for surgery should always be kept in mind, and early involvement of the surgical team is always encouraged. | – | Avoidance of life-threatening complications such as toxic megacolon, hemorrhage, and perforation is the goal of any treatment for fulminant ulcerative colitis. | |
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