TYPE 1 CRYOGLOBULINAEMIA ASSOCIATED WITH A THYMIC TUMOUR: SUCCESSFUL TREATMENT WITH PLASMA EXCHANGE |
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| Authors: | ATHANASSIOU P; IOAKIMIDIS D; WESTON J; GEORGANAS K; KONTOMERKOS T; DAVIES K A |
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| Institution: | *Rheumatology Unit, Department of Medicine
 Department of Rheumatology, General Hospital of Athens Greece
 Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital London |
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| Abstract: | Thymic tumours are associated with a wide range of autoimmuneand haematological disorders, notably myasthenia gravis, redcell aplasia, and systemic lupus erythematosus. An associationwith cryoglobulinaemia has only once been reported previously.In this report we describe a 60-yr-old male patient with a spindlecell thymoma, treated surgically, who also had type 1 cryoglobulinaemia,with severe peripheral circulatory impairment with digital ulcerationand a mononeutitis multiplex. The patient has been successfullytreated with prednisolone, immunosuppression and plasma exchange. KEY WORDS: Cryoglobulinaemia, Thymoma, Plasma exchange, Immunosuppression, Tumour, Corticosteroids |
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