补肾固肺膏配合呼吸运动对肺肾阳虚型慢性阻塞性肺疾病的影响

目的：评价补肾固肺膏配合呼吸运动治疗肺肾阳虚型慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)的疗效。方法将符合入选标准的肺肾阳虚型COPD患者按随机数字表法分为治疗组(32例)和对照组(34例)，对照组采用西医规范治疗，治疗组在对照组基础上加服补肾固肺膏配合呼吸运动。观察2组治疗后临床证候积分、肺功能变化，以及治疗结束后10个月内急性发作次数、发作持续时间，评价临床疗效。结果治疗后，治疗组证候积分(5.32±2.67)分比(9.12±4.11)分， t＝4.424]低于对照组(P＜0.01)；治疗组用力肺活量(3.00±0.49)L比(2.71±0.47)L，t＝2.408]、第1秒用力呼气容积(2.27±0.44)L比(1.85±0.54)L，t＝3.496]、第1秒用力呼气容积占预计值百分比(75.62±6.84)比(66.86±9.32)，t＝4.333]高于对照组(P＜0.05)。治疗结束后10个月，治疗组急性发作＞6次者9例，明显低于对照组的20例(χ2＝5.122，P＜0.05)，且急性发作持续时间(5.56±1.45)d比(8.06±1.80)d，t＝6.190]较对照组缩短(P＜0.01)。结论补肾固肺膏配合呼吸运动可有效改善肺肾阳虚型COPD患者的肺功能，提高患者生活质量，疗效优于单纯西医治疗。

The effects of Bushen-Gufeigao and breathing movements on the patients with COPD of ;lung and kidney yang deficiency TCM pattern

Objective Evaluating the effects of Bushen-Gufeigao and breathing movements on the patients with chronic obstructive pulmonary disease of Lung and kidney deficiency TCM pattern. Methods The patients with chronic obstructive pulmonary disease of lung and kidney deficiency TCM pattern were recruited and randomly divided into two groups the treatment group (32 cases) and the control group (34 cases). The control group was treated with the conventional medicine, and the treatment group were added Bufei-Gushengao and breathing movements based on the treatment of control group. Both groups were treated for 1 month. The changes of the clinical symptoms, lung function and frequency of attack and duration of each attack in 10 months after treatment were observed. Results After the treatment, compared with the control group, the TCM patterns scores (5.32 ± 2.67 vs. 9.12 ± 4.11, t=4.424) of the treatment group significantly decreased, while the FVC (3.00 ± 0.49 L vs. 2.71 ± 0.47 L, t=2.408), FEV1 (2.27 ± 0.44 L vs. 1.85 ± 0.54 L, t=3.496), and the percentage of FEV1%(75.62 ± 6.84 vs. 66.86 ± 9.32, t=4.333) increased significantly. In the 10 mouths after the treatment, the treatment group showed significantly fewer patients who had attacked more than 6 times than that in the control group, and the duration of attacks showed significantly fewer minutes in the treatment group than the control group (5.56 ± 1.45 d vs. 8.06 ± 1.80 d, t=6.190). Conclusion Bushen-Gufeigao and breathing movements can effectively improve patient's lung function and symptoms.