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血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂在慢性心力衰竭治疗中的应用
引用本文:居海宁,卞金陵. 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂在慢性心力衰竭治疗中的应用[J]. 药学服务与研究, 2011, 11(5): 377-381. DOI: 10.5428/pcar20110519
作者姓名:居海宁  卞金陵
作者单位:1. 第二军医大学长海医院预防保健科,上海200433;上海第七人民医院心血管内科,上海200137
2. 第二军医大学长海医院预防保健科,上海,200433
摘    要:心力衰竭是多种心脏病的最终死亡原因,阻断肾素-血管紧张素-醛固酮系统(renin angiotensin aldosterone system,RAAS)是减慢心力衰竭病变进展的主要策略。血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitors,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blockers,ARB)是目前最常用的阻断RAAS的药物。本文对慢性心力衰竭评估,以及ACEI和ARB在慢性心力衰竭治疗中的应用进行综述。

关 键 词:心力衰竭  血管紧张素转换酶抑制剂  血管紧张素受体拮抗剂  综述

Applications of angiotensin converting enzyme inhibitors and angiotensin receptor blockers in the treatment of chronic heart failure
JU HaiNing,BIAN JinLing. Applications of angiotensin converting enzyme inhibitors and angiotensin receptor blockers in the treatment of chronic heart failure[J]. Pharmaceutical Care and Research, 2011, 11(5): 377-381. DOI: 10.5428/pcar20110519
Authors:JU HaiNing  BIAN JinLing
Affiliation:JU HaiNing1,2,BIAN JinLing1(1.Department of Prevention and Health Care,Changhai Hospital,Second Military Medical University,Shanghai 200433,China,2.Department of Cardiovasology,the Seventh People's Hospital of Shanghai,Shanghai 200137,China)
Abstract:Heart failure is the ultimate cause of death in a variety of heart diseases.It has been discovered that the main strategy of slowing the progress of heart failure diseases is blocking the renin angiotensin aldosterone system(RAAS).Angiotensin converting enzyme inhibitors(ACEI) and angiotensin receptor blockers(ARB) are the most commonly used RAAS-blocking drugs.In this paper,the assessment of chronic heart failure and the applications of ACEI and ARB in the treatment of chronic heart failure are reviewed.
Keywords:heart failure  angiotensin converting enzyme inhibitors  angiotensin receptor block ers  review  
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