| 多糖及其衍生物在药物传递系统中的应用研究新进展 |
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| 引用本文： | 张文婕,范颖. 多糖及其衍生物在药物传递系统中的应用研究新进展[J]. 药学进展, 2011, 35(11): 496-503 |
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| 作者姓名： | 张文婕 范颖 |
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| 作者单位： | 1. 中国药科大学新药研究中心,江苏南京,210009
2. 上海医药工业研究院上海呼吸系统药物工程技术研究中心,上海,200437 |
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| 摘 要： | 多糖是一类生物相容性好、无毒、非免疫原性的生物材料,现已广泛应用于药物传递系统。综述海藻酸盐、几丁质、葡聚糖、透明质酸和肝素等多糖及其衍生物的理化和生物学特性以及在药物传递系统中的应用进展。
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| 关 键 词： | 多糖 药物传递系统 药物控释 |
New Advances in Application of Polysaccharides and Their Derivatives in Drug Delivery System |
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| ZHANG Wen-jie,FAN Ying. New Advances in Application of Polysaccharides and Their Derivatives in Drug Delivery System[J]. Progress in Pharmaceutical Sciences, 2011, 35(11): 496-503 |
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| Authors: | ZHANG Wen-jie FAN Ying |
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| Affiliation: | ZHANG Wen-jie1,FAN Ying2 (1.Center of Drug Discovery,China Pharmaceutical University,Nanjing 210009,China,2.Shanghai Engineering and Research Center for Respiratory System Drug,Shanghai Institute of Pharmaceutical Industry,Shanghai 200437,China) |
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| Abstract: | Polysaccharides,which are biocompatible,non-toxic and non-immunogenic,have been widely used as biomaterials in drug delivery system.The physico-chemical and biological properties of polysaccharides,such as alginate,chitin,dextran,hyaluronic acid,heparin,and their derivatives as well as the application in drug delivery system were reviewed. |
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| Keywords: | polysaccharides drug delivery system drug controlled release |
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