| 厚朴酚与和厚朴酚的体内药物分析方法及药代动力学研究近况 |
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| 引用本文： | 王丹,冯芳.厚朴酚与和厚朴酚的体内药物分析方法及药代动力学研究近况[J].药学进展,2011,35(9):396-400. |
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| 作者姓名： | 王丹 冯芳 |
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| 作者单位： | 中国药科大学药物分析教研室,江苏南京,210009 |
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| 摘 要： | 厚朴酚与和厚朴酚是中药厚朴的主要药效成分,具有多种药理作用,研究其药代动力学过程,对指导临床用药具有现实意义,而适宜的体内药物分析方法的建立,是成功进行药代动力学研究的基础。分类介绍厚朴酚与和厚朴酚的体内药物分析方法,综述并探讨其药代动力学的影响因素。
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| 关 键 词： | 厚朴酚 和厚朴酚 体内药物分析 药代动力学 |
Progress in Biopharmaceutical Analysis Methods and Pharmacokinetic Studies of Magnolol and Honokiol |
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| WANG Dan,FENG Fang.Progress in Biopharmaceutical Analysis Methods and Pharmacokinetic Studies of Magnolol and Honokiol[J].Progress in Pharmaceutical Sciences,2011,35(9):396-400. |
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| Authors: | WANG Dan FENG Fang |
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| Institution: | WANG Dan,FENG Fang(Department of Pharmaceutical Analysis,China Pharmaceutical University,Nanjing 210009,China) |
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| Abstract: | Magnolol(MN) and honokiol(HN),principal active components from Magnolia officinalis Rehd.et Wils.,exert multiple pharmacological actions.The study on their pharmacokinetics could be helpful to guide the clinical medication.The success in the study is based on the establishment of a good biopharmaceutical analysis method.The biopharmaceutical analysis methods for MN and HN were classifiedly introduced.The influencing factors on their pharmacokinetics were reviewed and discussed. |
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| Keywords: | magnolol honokiol biopharmaceutical analysis pharmacokinetics |
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