| 转化生长因子β与视网膜病变 |
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| 引用本文： | 刘照耀,彭辉灿,燕建军,王俞方. 转化生长因子β与视网膜病变[J]. 国际眼科杂志, 2008, 8(9): 1891-1893 |
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| 作者姓名： | 刘照耀 彭辉灿 燕建军 王俞方 |
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| 作者单位： | 南华大学附属第二医院眼科,中国湖南省衡阳市,421001 |
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| 摘 要： | 转化生长因子β(transforming growth factor β,TGF-β)是一类具有多种生物学功能的多肽生长因子,能调节多种细胞的生长、分化和移行,参与细胞外基质成分的合成和免疫调节,它不仅是正常眼内组织代谢及功能的基本因素,在许多眼内病理过程中它也起着重要作用。文章就TGF-β的结构、功能以及它与视网膜疾病关系作一简要综述。
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| 关 键 词： | 转化生长因子β 视网膜病变 |
Transforming growth factor-β and retinopathy |
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| Zhao-Yao Liu,Hui-Can Peng,Jian-Jun Yan,Yu-Fang Wang. Transforming growth factor-β and retinopathy[J]. International Eye Science, 2008, 8(9): 1891-1893 |
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| Authors: | Zhao-Yao Liu Hui-Can Peng Jian-Jun Yan Yu-Fang Wang |
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| Affiliation: | Department of Ophthalmology, the Second Affiliated Hospital of Nanhua University, Hengyang 421001, Hunan Province, China |
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| Abstract: | Transforming growth factor-β(TGF-β) is a kind of polypeptide growth factor with multiple of biological functions. TGF-β can adjust many kinds of cells’ growth, differentiation and migration, and participates extracellu-lar matrix’s synthesis and immunological regulation. TGF-β is not only the basic factor of the normal eye function and metabolism, also plays an important role in many pathological processes. We composed a brief overview about TGF-β’s construction, function and its relation with retinal disease. |
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| Keywords: | transforming growth factor-β retinopathy |
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