供体抗原经门静脉处理及移植物从门静脉回流对大鼠胰腺移植物功能存活的影响

以35只雄性SD大鼠为受体，制成糖尿病模型，以同龄Wistar雄性大鼠为供体，行全胰腺移植。供体抗原分别经门静脉或周围静脉处理，处理时间分别为移植前预处理或移植时处理，移植物静脉分别从门静脉或下腔静脉回流，结果表明供体抗原经门静脉预处理及移植物从门静脉回流对胰腺移植物功能存活的延长具有协同效应，移植时处理延长胰腺移植物效果不如移植前预处理，但可能具有一定的实用意义。

Effects of donor antigen treatment and graft venous drainage on pancreas graft survival

Wistar-to-SD rat pancreas transplantation was performed in 35 SD rat recipients with diabetes-induced. Denor antigen was administered through IV or PV and the antigen treatment was performed before or during the transplantation. Graft vein was drained into IV or PV.The results showed that donor antigen pretreatment via PV combined with graft drainage PV synergistically prolongs the pancreas graft survival, and the effect of simultananeous antigen treatment during transplantation is not as satisfactory as that of antigen pretreatment, but may be more practical.