| 脑梗死患者血清髓鞘碱性蛋白含量与脑实质损害的相关性 |
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| 引用本文： | 张国元,王晓明,唐中,郭晓兰,龙存国,廖涛.脑梗死患者血清髓鞘碱性蛋白含量与脑实质损害的相关性[J].中国组织工程研究与临床康复,2004,8(4):766-767. |
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| 作者姓名： | 张国元 王晓明 唐中 郭晓兰 龙存国 廖涛 |
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| 作者单位： | 1. 川北医学院附属医院,检验科,四川省,南充市,637000
2. 川北医学院附属医院,神经内科,四川省,南充市,637000 |
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| 摘 要： | 目的通过检测脑梗死患者及正常人的血清髓鞘碱性蛋白(myelin
basic protein,MBP)的含量,探讨脑梗死患者血清髓鞘碱性蛋白含量与脑实质损害的相关性.方法采用双抗体夹心酶联免疫吸附法对32位正常人及30例脑梗死患者血清MBP含量进行了检测.结果脑梗死患者和对照组血清其MBP含量分别为(5.63±3.56),(1.10±0.45)μg/L,差异有极显著性(t=7.145,P＜0.001),且血清MBP含量与脑梗死体积有一定的关系.结论脑梗死时血清MBP含量明显升高,且与脑实质损害程度有一定的关系.
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| 关 键 词： | 脑梗塞/病理生理学 髓鞘 酶联免疫吸附测定 |
Correlation between myelin basic protein contents and cerebral parenchyma damages in cerebral infarction patients |
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| Abstract.Correlation between myelin basic protein contents and cerebral parenchyma damages in cerebral infarction patients[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2004,8(4):766-767. |
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| Authors: | Abstract |
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| Abstract: | AIM: To discuss the correlation between myelin basic protein(MBP) contents and cerebral parenchyma damages in cerebral infarction patients through the assay of MBP contents in both cerebral infarction patients and healthy subjects.METHODS: The MBP serous contents of 32 healthy subjects and 30 cerebral infarction patients were detected by double-antibody-filling ELISA.RESULTS: The serous MBP contents of healthy subjects and cerebral infarction patients were(5.63 + 3.56) and(1.10 + 0.45) μg/L respectively.There was significance between the patient group and the control group ( t = 7. 145, P ＜ 0. 001 ) . There was a certain relationship between the serous MBP content and the volume of cerebral infarct area.CONCLUSION: Serous MBP content markedly increases in cerebral infarction patients, and moreover, there is a certain relationship with the severity of cerebral parenchyma damage. |
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