三叉神经微血管减压术后颅内感染的多模式干预策略研究

目的探讨多模式干预策略对预防三叉神经微血管减压术后颅内感染的效果。方法选取中国科学技术大学附属第一医院神经外科2018年1～12月收治的三叉神经微血管减压术患者117例为研究对象,根据随机数字表法分为观察组(n=62)和对照组(n=55),对照组采取常规的感控措施,观察组实施多模式干预策略,干预6个月后,比较两组术后颅内感染发生率、平均住院日、平均住院费用等指标。结果观察组术后颅内感染率为1. 61%,低于对照组的12. 73%,差异有统计学意义(P <0. 05);观察组平均住院日为(21. 55±4. 24)天,低于对照组的(21. 80±5. 87)天,差异无统计学意义(P> 0. 05);观察组平均住院费用为(34 821. 15±5 563. 32)元,低于对照组的(37 272. 38±6 978. 09)元,差异有统计学意义(P <0. 05)。结论多模式干预策略可减少三叉神经微血管减压患者术后颅内感染发生率,降低患者的平均住院费用。

Study on multi-mode intervention strategy for intracranial infection after microvascular decompression of trigeminal nerve

Objective To investigate the effect of multi-mode intervention strategy on prevention of intracranial infection after microvascular decompression of trigeminal nerve. Methods A total of 117 patients with trigeminal microvascular decompression admitted to the Department of Neurosurgery of the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China from January to December 2018 were selected as the research objects. The patients were randomly divided into the observation group (n=62) and the control group (n=55). The control group adopted conventional infection control measures, while the observation group implemented multi-mode intervention strategies, then the incidence of postoperative intracranial infection, average length of stay, average hospitalization cost and other indicators were compared between the two groups. Results The postoperative intracranial infection rate in observation group was 1.61%, which was lower than that in control group (12.73%), and the difference was statistically significant (P<0.05). The mean length of stay in observation group was (21.55±4.24) days, which was lower than that of control group, and the difference was not statistically significant (P>0.05). The average hospitalization cost of observation group was (34 821.15±5 563.32) yuan, which was lower than that of control group, and the difference was statistically significant (P<0.05). Conclusion Multi-mode intervention strategy can reduce the incidence of intracranial infection in patients with trigeminal microvascular decompression and reduce the average hospitalization cost.