| Abstract: | It is often difficult to determine the actual site of origin of tumours originating in the sino‐nasal region, and a uniform classification system that covers all tumours in this area is warranted. A retrospective series of 165 consecutive patients with sino‐nasal carcinoma, treated and followed at the Aarhus University Hospital between 1963 and 1991, was evaluated and T‐staged according to the Lederman classification. The 80 maxillary antrum carcinomas were also staged according to the UICC 1997 system. In univariate analysis, the UICC T‐classification was prognostic for locoregional tumour control and disease‐specific survival. However, when adjusted for covariates (gender and nodal involvement) in a multivariate analysis, the UICC classification was not a significant independent prognostic parameter. In contrast, the Lederman T‐classification was prognostic both in univariate and multivariate analysis. The Lederman T‐classification was more prognostic for locoregional control and disease‐specific survival than the UICC TNM classification. In addition, the Lederman classification is easy to use and has a broader applicability as it covers all sites in the sino‐nasal area. |
