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半枝莲黄酮类化学成分分析
引用本文:汪琛媛,段贤春,李瑛,汪永忠.半枝莲黄酮类化学成分分析[J].安徽医学,2019,40(8):848-851.
作者姓名:汪琛媛  段贤春  李瑛  汪永忠
作者单位:230031,合肥 安徽中医药大学第一附属医院药学部;230031,合肥 安徽中医药大学第一附属医院药学部;230031,合肥 安徽中医药大学第一附属医院药学部;230031,合肥 安徽中医药大学第一附属医院药学部
基金项目:安徽省高校优秀拔尖人才培育资助项目(项目编号:gxyq2019034)
摘    要:目的分析半枝莲黄酮类化学成分。方法采用硅胶、Sephadex LH-20等多种色谱方法,依据波谱数据对其结构进行分析和鉴定。结果半枝莲中共分离了12个化合物,分别为圣草酚、野黄芩素、三裂鼠尾草素、黄芩苷、芹菜素、汉黄芩素、4'-羟基汉黄芩素、木犀草素、4',5-二羟基-3',5',6,7-四甲氧基黄酮、柚皮素、7-羟基-5,8,2'-三甲氧基黄烷酮、大波斯菊苷。结论分离得到的化合物类型均为黄酮苷元和苷类化合物,可为半枝莲的黄酮成分分析提供一定的科学依据。

关 键 词:半枝莲  化学成分  黄酮
收稿时间:2018/12/26 0:00:00

Studies on chemical constituents of flavonoids from Scutellaria barbata
WANG Chenyuan,DUAN Xianchun,LI Ying.Studies on chemical constituents of flavonoids from Scutellaria barbata[J].Anhui Medical Journal,2019,40(8):848-851.
Authors:WANG Chenyuan  DUAN Xianchun  LI Ying
Institution:Department of Pharmacy, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China,Department of Pharmacy, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China,Department of Pharmacy, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China and Department of Pharmacy, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China
Abstract:Objective To study the chemical constituents of flavonoids from Scutellaria barbata. Methods A review on the silica gel columm and Sephadex LH-20 were summarized based on the spectral data. Results Twelve flavonoids were isolated from Scutellaria Barbata, eriodictyol, scutellarein, salvigenin, baicalin, apigenin, wogonin, 4''-hydroxywogonin, luteolin, 4'',5-dihydroxy-3'',5'',6,7-tetramethoxyflavone, naringenin, 7-hydroxy-2'',5,8-trimethoxyflavanone, cosmosiin, respectively. Conclusions All compounds are flavonoids, including flavonoid aglycones and glycosides. It may provide scientific basis for the analysis of flavonoids from Scutellaria barbata.
Keywords:Scutellaria barbata  Chemical constituents  Flavonoids
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