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Characteristics of the formation of systems activity in the brain and autonomic functions in children in conditions of the European North (discussion paper)
Authors:S. I. Soroko  É. A. Burykh  S. S. Bekshaev  G. V. Sidorenko  E. G. Sergeeva  A. E. Khovanskikh  B. N. Kormilitsyn  S. N. Moralev  O. V. Yagodina  L. K. Dobrodeeva  I. A. Maksimova  O. V. Protasova
Affiliation:(1) Interinstitute Laboratory for Comparative Ecological-Physiological Studies, I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry and North-East Scientific Center, Far Eastern Branch, Russian Academy of Sciences, 44 Torez Prospekt, 194223 St. Petersburg, Russia;(2) Functional Biochemistry Laboratory, I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Torez Prospekt, 194223 St. Petersburg, Russia;(3) Department of Ecological Immunology, Institute of the Physiology of Natural Adaptation, Urals Branch, Russian Academy of Sciences, 249 Lomonosov Prospekt, 163061 Arkhangel’sk, Russia;(4) Medical Biophysics Laboratory, N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, 4 Kosygin Street, 117977 Moscow
Abstract:Results obtained from complex medical-physiological investigations performed during 10 scientific expeditions in the Arkhangel’sk Region in 2003–2005 are presented. The effects of climatological-geographic, biogeochemical, and social conditions of the conditions obtaining in the Far North region of Russia on sexual maturation, formation of the structural-functional organization of the brain, autonomic functions, and immunological and biochemical status of schoolchildren were studied using state-of-the-art neurophysiological methods (computerized electroencephalography, computerized rheoencephalography, computerized electric dipole origin tomography, etc.), psychophysiological and psychometric methods (assessment of the state of cognitive and memory functions, Wechsler intellectual scale), along with biochemical assay of monoamine oxidase (MAO, the key enzyme in adrenergic neurotransmitter metabolism) and the liver enzyme butyrylcholinesterase (BuChE) and physicochemical analysis of the levels of macroelements and trace elements in the body. __________ Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 92, No. 8, pp. 905–929, August, 2006.
Keywords:adaptation  brain  children  delayed mental development  immune system  intellect  sexual development  macroelements  trace elements  EEG  extreme conditions in the North
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