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国产法莫替丁治疗消化性溃疡的近期疗效观察
引用本文:曲波,于春先,李秀蓉,傅国华,范翠红,李连宏.国产法莫替丁治疗消化性溃疡的近期疗效观察[J].大连医科大学学报,1990(1).
作者姓名:曲波  于春先  李秀蓉  傅国华  范翠红  李连宏
作者单位:大连医学院附属二院,大连医学院附属二院,大连医学院附属二院,大连医学院附属二院,大连医学院附属二院,大连医学院病理教研室
摘    要:本文报告应用国产法莫替丁治疗消化性溃疡45例的近期疗效。治疗组法莫替丁20mg,早晚各服一次;对照组甲氰咪胍400mg,早晚各服一次,两组疗程皆为6周。以胃镜检查为诊断和评价疗效的依据,两组愈合率分别为97.8%,89.9%,上腹疼痛用药后三日缓解率分别为60.9%,30.2%。两组均未出现明显毒副作用,由于抗溃疡新药疗效高,提示今后治疗无合并症消化性溃疡将以药物治疗为主。

关 键 词:消化性溃疡  法莫替丁  甲氰咪胍

SHORT TERM EFFICACY OF FAMOTIDINE IN THE TREATMENT OF PEPTIC ULCER
QU BO.SHORT TERM EFFICACY OF FAMOTIDINE IN THE TREATMENT OF PEPTIC ULCER[J].Journal of Dalian Medical University,1990(1).
Authors:QU BO
Institution:QU BO Department of Medicine,Second Affiliated Hospital,Dalian Medical College
Abstract:From May to September this year,90 cases of peptic ulcer were treated with famotidine and cimetidine,45 cases respectively.We used famotidine 20mg twice daily compared with cimetidine 400mg twice daily orally in treating peptic ulcer.The course is 6 weeks.The diagnosis of peptic ulcer and the evaluation of efficacy were based on gastroscopy.The result has shown that the healing rate in the two groups was 97.8% and 89.9% respectively.There was significant difference between the two groups.In group 1,patients with epigastric pain disappeared within 3 days were about 60.9% and in group 2 it was 30.2% only.Therefore we think that the efficacy of famotidine is superior to that of cimetidine.Using famotidine will greatly decrease the chance of operation for the treatment of peptic ulcer without complication.
Keywords:peptic ulcer  famotidine  cimetidine
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