| 艰难梭菌感染的诊断及治疗研究进展 |
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| 引用本文： | 季欣欣,孟秀娟,任南,黄勇.艰难梭菌感染的诊断及治疗研究进展[J].中国感染控制杂志,2019,18(6):600-606. |
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| 作者姓名： | 季欣欣 孟秀娟 任南 黄勇 |
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| 作者单位： | 艰难梭菌感染的诊断及治疗研究进展 |
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| 基金项目： | 国家自然科学基金面上项目（81473123） |
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| 摘 要： | 艰难梭菌是一种革兰阳性厌氧芽孢杆菌,现已成为全球分布的主要肠道病原体。艰难梭菌感染(Clostridium difficile infection,CDI)可引起抗菌药物相关性腹泻,而其严重感染会导致假膜性结肠炎和中毒性巨结肠等严重并发症。CDI正成为全世界公共卫生的一个持续挑战。本文就近年来国内外CDI的诊断、预防和治疗予以简要综述,为防治CDI提供依据。
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| 关 键 词： | 艰难梭菌 毒素 感染 危险因素 肠道菌群 |
| 收稿时间： | 2019-04-25 |
Advances in diagnosis and treatment of Clostridium difficile infection |
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| JI Xin-xin,MENG Xiu-juan,REN Nan,HUANG Yong.Advances in diagnosis and treatment of Clostridium difficile infection[J].Chinese Journal of Infection Control,2019,18(6):600-606. |
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| Authors: | JI Xin-xin MENG Xiu-juan REN Nan HUANG Yong |
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| Institution: | 1. Xiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China;2. Center for Healthcare-associated Infection Control, Xiangya Hospital, Central South University, Changsha 410008, China;3. National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery, Changsha 410205, China |
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| Abstract: | Clostridium difficile (C. difficile) is a gram-positive anaerobic bacillus and has become a major intestinal pathogen worldwide. C. difficile infection (CDI) can cause antimicrobial-associated diarrhea, severe infection may lead to severe complications such as pseudomembranous colitis and toxic megacolon. CDI is becoming a continuing challenge to public health worldwide. In this paper, the diagnosis, prevention and treatment of CDI at home and abroad in recent years are briefly reviewed, so as to provide a basis for the prevention and treatment of CDI. |
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| Keywords: | Clostridium difficile toxin infection risk factor intestinal flora |
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