Prevention of central line-associated bloodstream infections in the neonatal intensive care unit: A literature review期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Prevention of central line-associated bloodstream infections in the neonatal intensive care unit: A literature review

Affiliation:	1. Department of Pediatrics, The Ohio State University, Columbus, OH;2. Nationwide Children''s Hospital, Columbus, OH;1. Department of Pediatrics, Columbia University Medical Center, New York, NY;2. Department of Infection Prevention and Control, NewYork-Presbyterian Hospital, New York, NY;3. Department of Medicine, Columbia University Medical Center, New York, NY;4. RAND Corporation, Boston, MA;5. Center for Health Policy, Columbia University School of Nursing, New York, NY;1. Department of Neonatology, Children''s Hospital of Fudan University, Shanghai, China;2. Department of Pediatrics, University of Toronto, Toronto, ON, Canada;3. Department of Microbiology, Children''s Hospital of Fudan University, Shanghai, China;1. Mayo Clinic Health Care System, Eau Claire, WI, USA;2. Ministry of Health, Oman;3. University of Stellenbosch, Cape Town, South Africa;4. Prince Mohammed bin Abdulaziz Hospital, Riyadh, Saudi Arabia;5. Infection Control Consortium (INICC), Buenos Aires, Argentina;6. The Chinese University of Hong Kong, Hong Kong, China;7. US Naval Medical Research, Egypt;8. Stellenbosch University, Cape Town, South Africa;9. VCU Medical Center, Richmond, VA, USA

Abstract:	Central line-associated bloodstream infections are a significant patient safety issue for newborns in the neonatal intensive care unit. Preventing these devastating and costly infections is a global priority for health organisations and key to minimising harm for this vulnerable population. The aim of this literature review is to explore and identify evidence-based prevention strategies for central line-associated blood stream infections in neonates. Thematic analysis of the literature revealed four effective prevention strategies: central line care bundles, consistent education, regular surveillance and dedicated vascular access teams. Evidence suggests that a combination of these evidence-based interventions is the most effective strategy; however, future research is required to establish the preferred skin antiseptic and to continue exploring new prevention strategies.

Keywords:	Central line-associated bloodstream infection (CLABSI) Prevention strategy Central line Neonate Neonatal intensive care unit (NICU)
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