Entheses ultrasound assessment in primary Sjogren's syndrome |
| |
| Institution: | 1. Faculty of Medecine of Tunis, University of Tunis El Manar, 2046 Tunis, Tunisia;2. Rheumatology department, Mongi Slim hospital, La Marsa, 2046 Tunis, Tunisia;1. Centre d’Évaluation et Traitement de la Douleur, Hôpital Cochin, Université Paris Descartes, 75014 Paris, France;2. INSERM U987, 92100 Boulogne Billancourt, France;3. EA 7537, Faculté de pharmacie de Paris, Université Paris Descartes, 75006 Paris, France;4. Service de biostatistiques et d’informatique médicales, hôpital Saint-Louis, Assistance publique–hôpitaux de Paris, 75010 Paris, France;5. Association Française des Polyarthritiques (AFP Ric), 9, rue de Nemours, 75011 Paris, France;1. Epidemiology and Biostatistics Unit, Sorbonne Paris Cité Research Center Inserm U1153, Paris, France;2. Department of Rheumatology, Cochin Hospital, Paris, France;3. Paris Descartes University, Paris, France;4. François-Rabelais University, CNRS 7292, Tours, France;5. Biostatistics and Clinical Epidemiology research, Inserm U1153, Paris Diderot University, Paris, France;1. Service de rhumatologie, CHU de Strasbourg, Strasbourg, France;2. Centre national de références des maladies systémiques et auto-immunes rares Est Sud-Ouest (RESO), université de Strasbourg, Strasbourg, France;1. Service de Rhumatologie et EA 4490, CHU Lille et Université de Lille, 59000 Lille, France;2. Service de Radiologie Ostéo-articulaire, CHU Lille, 59000 Lille, France;3. Service de Radiologie, Hôpital Lariboisière, Université de Paris et UMR 7052, 75475 Paris cedex 10, France;1. Rheumatology Unit Hospital, S. Giovanni di Dio, Azienda USL-Toscana Centro, Florence, Italy;2. Immunology and Allergology Laboratory Hospital S. Giovanni di Dio, Azienda USL-Toscana Centro, Florence, Italy;3. Clinic of Rheumatology, Department of Medicine (DAME), ASUFC, Udine, Italy |
| |
| Abstract: | ObjectiveMusculoskeletal pain is a common complaint among patients with primary Sjogren's syndrome (pSS). Joints clinical examination is oftenly normal. A periarticular origin of this pain may be possible. Since clinical examination lacks sensitivity and precision, the use of musculoskeletal ultrasound (US) is more interesting in the evaluation of the entheses involvement, as it is shown to be a more sensitive tool. Our objective was to assess, by an ultrasonographic study, the entheses involvement in the widespread pain of patients with pSS.MethodsThis is a prospective study including 25 women with pSS and 25 age and sex matched healthy controls. An ultrasound examination, using grey scale and Doppler US, of five enthesitic sites (distal quadricipital, proximal patellar, distal patellar, distal Achillian and distal brachial tricipital) sought bilaterally the following lesions: hypoechogenicity, thickening, loss of fibrillar structure, erosions, enthesophytes, calcifications or Doppler hypervascularisation. A final score was calculated by summing the abnormalities scores of all entheses.ResultsThe mean age was 53.2 ± 11.3 years in the pSS group and 50.6 ± 9.7 years in the control group. The mean number of pathological entheses on ultrasound was 3.92 ± 1.93 in the pSS group versus 4.52 ± 2.27 in the control group (P > 0.05). The total score for enthesitis abnormalities was 4.96 ± 2.59 versus 5.72 ± 2.92 (P > 0.05), respectively. There was a positive correlation between total score of ultrasound enthesitic abnormalities and age in both groups.ConclusionIn patients with pSS, clinically painful sites were more frequently found than in US. Musculoskeletal pain was not due to enthesitis. |
| |
| Keywords: | Ultrasonography Enthesis Sjogren's syndrome Diagnostic imaging Musculoskelateal pain |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
