正交试验优选紫百止嗽胶囊中紫菀的提取工艺

目的 筛选紫百止嗽胶囊中紫菀的最佳提取工艺。方法 采用正交设计试验，以紫菀酮提取率为指标，考察溶剂体积分数、溶剂用量倍数、提取时间、提取次数4个因素对提取结果的影响。结果 最佳提取工艺为药材质量8倍量80%乙醇、提取3次、每次60 min。结论 该工艺所得浸膏得率和紫菀酮提取率均较高，工艺稳定、重复性好，可为紫百止嗽胶囊的生产提供参考。

Optimization of extraction technology for Asteris Radix et Rhizoma in Zibai Zhisou Capsules with orthogonal test

Objective To optimize the extraction technology of Asteris Radix et Rhizoma in Zibai Zhisou Capsules. Methods Orthogonal test was carried out. The influences of concentration of solvent, the dosage of solvent, duration of extraction, and frequency of extraction on extraction results were investigated by using the content of shionons as index. Results The optimal extraction technique was to extract pueraria in 80% alcohol with 8 times the weight of herbal medicine for 3 times, with 60 min once. Conclusion High yield of extractum and high content of shionon are obtained with the present technology. The results with better repeatability are stable, which can provide the reference for the production of Zibai Zhisou Capsules.