First description of DHA-1 ampCβ-lactamase in Proteus mirabilis |
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| Authors: | P. Bidet C. Verdet V. Gautier E. Bingen G. Arlet |
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| Affiliation: | Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA 3105), Université Denis Diderot-Paris VII, Service de Microbiologie, H?pital Robert Debré, Paris, France. philippe.bidet@rdb.ap-hop-paris.fr |
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| Abstract: | This report describes the first occurrence of the DHA-1 ampCbeta-lactamase gene in Proteus mirabilis. The organism was isolated from the vaginal flora of a pregnant woman in a French hospital. The DHA-1 beta-lactamase gene was identified on the basis of phenotypic characteristics, PCR amplification and sequencing. Antagonism between cefoxitin and the other cephalosporins suggested inducible production of the DHA-1 enzyme. |
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| Keywords: | ampC β-lactamase class C β-lactamases DHA-1 Proteus mirabilis resistance |
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