| 亚砷酸联合维甲酸化疗治疗急性早幼粒细胞白血病疗效观察 |
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| 引用本文： | 闻艳. 亚砷酸联合维甲酸化疗治疗急性早幼粒细胞白血病疗效观察[J]. 河北医学, 2016, 0(9). DOI: 10.3969/j.issn.1006-6233.2016.09.010 |
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| 作者姓名： | 闻艳 |
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| 作者单位： | 云南省第一人民医院血液科,云南 昆明,650032 |
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| 基金项目： | 云南省医学学科带头人资助项目 |
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| 摘 要： | 目的：：研究急性早幼粒细胞白血病行亚砷酸和维甲酸、化疗联合治疗效果。方法：资料取本院2008年4月至2015年4月急性早幼粒细胞白血病90例患者予回顾分析，按治疗方案分成两组，对照组行维甲酸与化疗，观察组联合亚砷酸，对比两组疗效。结果：观察组早幼粒细胞比例与总白细胞数改善效果比对照组优( P<0.05)。结论：急性早幼粒细胞白血病患者行亚砷酸和维甲酸、化疗联合治疗效果满意。
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| 关 键 词： | 早幼粒细胞 急性 白血病 化疗 亚砷酸 维甲酸 |
The Efficacy of Arsenite Combined with Rretinoic Acid and Chemotherapy on Acute Promyelocytic Leukemia |
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| Abstract: | Objective: To observe the effect of arsenite combined retinoic acid and chemotherapy on treatment of acute promyelocytic leukemia. Methods:90 cases of acute early promyelocytic leukemia patients admitted in our hospital from April 2008 to April 2015 were selected to retrospective analyse, and according to the treatment plan was divided into two groups. The control group was treated with retinoic acid combined with chemotherapy, and the observation group was treated jointly arsenite. The curative effects of the two groups were compared. Results: The promyelocytic ratio and total number of white blood cells in the observation group improved than that in the control group ( P < 0.05) . Conclusion:For patients with acute promyelocytic leukemia,the treatment method of chemotherapy combined with arsenite and retinoic acid has a satisfactory effect. |
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| Keywords: | Promyelocytic Acute Leukemia Chemotherapy Arsenous acid Retinoic acid |
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