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动脉栓塞化疗联合射频消融治疗原发性肝癌临床疗效分析
引用本文:刘世峰.动脉栓塞化疗联合射频消融治疗原发性肝癌临床疗效分析[J].河北医学,2016(7):1109-1111.
作者姓名:刘世峰
作者单位:四川省自贡市第三人民医院肝胆外科,四川 自贡,643020
基金项目:四川省教育厅科研基金;(2013K12-01-23)
摘    要:目的::评价动脉栓塞化疗联合射频消融治疗原发性肝癌的疗效。方法:选取66例于2013年3月至2015年3月在我院肿瘤科住院治疗的原发性肝癌患者,遵照随机数字表法分层随机分为试验组和对照组各33例,入组的所有患者在治疗方案上均选取动脉栓塞化疗,且试验组患者同时加用射频消融治疗,比较不同治疗方案对患者肝功能的影响及2年后患者肿瘤的复发率。结果:治疗后试验组患者的肝功能指标改善程度明显高于对照组,差异有统计学意义( P <0.05);复发率则较对照组明显降低,差异有统计学意义(P<0.05)。结论:原发性肝癌患者采用动脉栓塞联合射频消融进行治疗,不仅能够显著的提高临床治疗效果保护患者的肝功能,而且降低术后复发率的发生,延长患者的生存期,疗效可靠,值得临床推广和应用。

关 键 词:原发性肝癌  射频消融术  动脉栓塞

Analysis of the Artery Embolism Chemotherapy with Radiofrequency Ablation Treatment of Primary Liver Cancer
Abstract:Objective: To research the value artery embolism chemotherapy with radiofrequency ablation therapy for primary liver cancer, in order to prolong the survival period and ease the pain of the patients. Methods: 66 cases with primary liver cancer, which admitted in our hospital oncology department from March 2013 to March 2015, were selected as the research object according to random number table method and divid-ed into experimental group and control group, each group of 33 cases, according to the principle of double blind control. All the patients were selected artery embolization chemotherapy, while the experimental group patients treated with radiofrequency ablation at the same time. The effect of liver function and patients with tumor recurrence after 2 years of the two groups were compared. Results:It found that the total bilirubin, the comparison of two groups with difference was statistically significant (P <0.05). The recurrence rate after 2 years of the experimental group was 3 / 25 (12.00%) and that of the control group was 3 / 7 (42.86%);the difference was significant statistically significant (P<0.05). Conclusion: The artery embolism chemotherapy with radiofrequency ablation therapy on the treatment of primary liver cancer not only can significantly improve the clinical therapeutic effect, but also reduce the postoperative recurrence rate and prolong survival in patients with stage; the curative effect is reliable, which is worthy of clinical popularization and application.
Keywords:Primary liver cancer  Radiofrequency ablation  Artery embolization
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