Assessment of residual coronary arterial stenosis after thrombolytic therapy during acute myocardial infarction |
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| Authors: | L F Satler R S Pallas O B Bond C E Green D L Pearle G L Schaer K M Kent C E Rackley |
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| Affiliation: | 1. Queensland Centre for Advanced Materials Processing and Manufacturing (AMPAM), The University of Queensland, Australia;2. School of Science and Engineering, University of the Sunshine Coast, Queensland 4575, Australia;1. Department of Motor Vehicles and Transportation Technology, Aksaray University, Aksaray 68100, Turkey;2. Department of Aerospace Engineering, Erciyes University, Kayseri 38280, Turkey;1. Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China;2. Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China;3. National & Local Joint Engineering Laboratory for Motive Power and Key Materials, College of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China;4. Advanced Research Institute for Multidisciplinary Science, Beijing Institute of Technology, Beijing 100081, China |
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| Abstract: | Maximal myocardial salvage appears to be related to the severity of residual coronary arterial stenosis after thrombolysis. The degree of residual infarct vessel stenosis was assessed in 119 consecutive patients with patent arteries who received streptokinase during acute myocardial infarction. After administration of streptokinase, 99 of 119 patients (83%) had a residual stenosis 70% or more in diameter. Assuming that a residual diameter stenosis of at least 70% is flow limiting, the feasibility for percutaneous transluminal coronary angioplasty (PTCA) was determined by the following criteria: length less than 10 mm, no significant distal narrowing or left main stenosis, and an adequate-sized distal artery. In 81 of 99 patients (82%), arterial anatomy was suitable for PTCA. Thus, after therapy with streptokinase for acute myocardial infarction, most patients have a significant infarct arterial residual stenosis and are candidates for PTCA. |
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