正电子发射断层摄影术在头颈部恶性肿瘤诊断中的应用

目的 :探讨18F FDG正电子发射断层摄影术 (PET)在头颈部恶性肿瘤诊断中的价值。方法 :回顾性分析应用18F FDGPET检查的 75例头颈部肿瘤患者 (鼻咽癌 36例 ,食管癌 18例 ,甲状腺癌 13例 ,喉癌 6例 ,下咽癌 2例 )的临床资料 ,其18F FDGPET显像结果与病理结果进行比较 ,部分与CT、MRI比较。结果 :18F FDGPET显像结果与病理结果相符率极高 ,鼻咽癌的灵敏度为 91.30 % ,特异度为 76 .92 % ,准确率为 86 .11% ;食管癌的灵敏度为 10 0 .0 0 % ,特异度为 83.33% ,准确率为 94 .4 4 % ;甲状腺癌、喉癌和下咽癌的灵敏度、特异度及准确率均为 10 0 %。结论 :18F FDGPET在头颈部恶性肿瘤的诊断中具有明显的优势。

18F-FDG PET in the diagnosis of head and neck tumor

Objective:To analyze the value of 18 F FDG PET in the diagnosis of patients suspected of having head and neck malignant tumor.Method:Seventy five cases patients suspected of having head and neck cancer or recurrence were analyzed retrospectively. 18 F FDG PET was performed in all cases.The results of some cases were compared with CT and MRI.Result: 18 F FDG PET yielded a sensitivity 91.30 % and specificity 76.92 % and accuracy 86.11 % in the diagnosis of nasopharyngeal carcinoma; sensitivity 100.00 % and specificity 83.33 % and accuracy 94.44 % in esophageal carcinoma; sensitivity and specificit and accuracy 100% in thyroid carcinoma,laryngeal carcinoma and hypopharyngeal carcinoma.Conclusion:Preliminary clinical application of 18 F FDG PET has demonstrated its significant advantages in evaluating head and neck malignant diseases.