Fluconazole levels in plasma and vaginal secretions of patients after a 150-milligram single oral dose and rate of eradication of infection in vaginal candidiasis. |
| |
Authors: | E T Houang O Chappatte D Byrne P V Macrae J E Thorpe |
| |
Affiliation: | Queen Charlotte's and Chelsea Hospital for Women, London, United Kingdom. |
| |
Abstract: | Mean peak concentrations of fluconazole in plasma and vaginal secretions of females after a 150-mg single oral dose were shown to be 2.82 micrograms/ml and 2.43 micrograms/g, respectively. Our results indicate that clinically efficacious concentrations of fluconazole in vaginal secretions are easily achieved after this single oral dose. |
| |
Keywords: | |
|