| ZT胶作为门静脉栓塞材料的实验研究 |
| |
| 引用本文： | 庄树彤,;陈斌,;倪勇,;周汝明,;高海斌. ZT胶作为门静脉栓塞材料的实验研究[J]. 广东寄生虫学会年报, 2007, 0(10): 962-964 |
| |
| 作者姓名： | 庄树彤, 陈斌, 倪勇, 周汝明, 高海斌 |
| |
| 作者单位： | [1]深圳市第二人民医院普外科,深圳518035; [2]深圳市第二人民医院放射科,深圳518035 |
| |
| 基金项目： | 深圳市卫生局科技资助项目（No.200104093）. |
| |
| 摘 要： | 目的探讨ZT胶行兔选择性门静脉栓塞（SPVE）的安全性及有效性。方法新西兰白兔24只，随机分为3组，A组为ZT胶：碘油（1：1）混合物组，B组为ZT胶：碘油（1：2）混合物组，对照组C组为碘油组。对各组门静脉左支进行SPVE，术后检测门静脉压力、肝转氨酶（ALT、AST）的变化，术后30d右肝重／全肝重、全肝重／体重。结果SPVE后门静脉压力、肝转氨酶呈一过性升高；栓塞后肝左叶萎缩、纤维化，肝右叶代偿性增生肥大．右肝重／全肝重B组为69．41％，而C组为39．00％。统计学分析显示，B组栓塞效果明显优于其他组（P〈0．05）。结论ZT胶：碘油（1：2）混合物是一种安全、有效的门静脉栓塞材料。
|
| 关 键 词： | ZT胶 门静脉栓塞 安全性 有效性 |
Experimental Study of ZT Glue As An Embolic Agent on Portal Vein |
| |
| Affiliation: | ZHUANG Shu-tong,CHEN Bin,NI Yong, ZHOU Ru-ming, GAO Hai-bin (Department of General Surgery, the Second Hospital of Shenzhen, Shenzhen 518035, China) |
| |
| Abstract: | Objective To evaluate the safety and efficacy of selective portal vein embolization （SPVE） with ZT glue in rabbit. Method Twenty-four white New Zealand rabbits were randomly divided into 3 groups. Group A received SPVE of the left branch （ZT glue ： lipiodol = 1 ： 1 ）. Group B received SPVC of the left branch （ZT glue ： lipiodol = 1 ： 2）. Group C only received lipiodol. Portal venous pressure, ALT, and AST were measured before and after SPVE. The weight of the right lobe, the whole liver, and the whole body at day-30 after SPVE were recorded and analyzed. Result A transient elevation in portal venous pressure and serum aminotransferase level was observed. Atrophy of the embolized lobes and compensatory hypertrophy of the non-embolized lobes were observed after SPVE. The weight ratios of the right lobe to the whole liver is 69.41% in group B. The best result was observed in Group B （P 〈 0.05）. Conclusion A mixture of ZT glue containing ZT-lipiedol （1 ： 2） is safe and effective in portal vein embolization. |
| |
| Keywords: | ZT glue portal vein embolization safety efficacy |
| 本文献已被 维普 等数据库收录！ |
|
