红霉素与阿奇霉素转换疗法治疗小儿肺炎支原体肺炎的疗效及成本分析

目的探讨转换疗法治疗小儿肺炎支原体肺炎的最佳方案。方法将102例患儿分为两组。治疗组5％葡萄糖＋红霉素静滴3d，改用阿奇霉素口服3d，停4d，再服3d；对照组5％葡萄糖＋红霉素静滴10～14d。观察疗效及成本分析。结果治疗组与对照组疗效与成本差异显著。结论治疗组疗效及成本明显优于对照组，且有效、安全、方便、经济。

Efficacy of Combination Therapy of Infantile Mycoplasma Pneumonia with Erythromycin and Azithromycin

Objective To evaluate the efficacy of combination therapy of infantile pneumonia caused by mycoplasma infection with erythromycin and azithromycin. Methods 102 subjects with infantile pneumonia were divided into 2 groups. The patients in the treatment group were treated （i.v） with erythromycin in 5% glucose for 3 days, then twice with azithromycin for 3 days by oral intake, with an interval of resting for 4 days. Patients in the control group were treated （i.v） with erythromycin in 5 % glucose for 10 to 14 days. Cost-effectiveness analysis was performed. Results A significant difference in the effectiveness of combination therapy was observed （P〈0.01）. Conclusion The combination therapy is safe and cost effective in treating infantile pneumonia caused by mycoplasma.