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HP与MVP方案治疗晚期非小细胞肺癌比较
引用本文:周忠,高兴亚,林艳华.HP与MVP方案治疗晚期非小细胞肺癌比较[J].肿瘤学杂志,2004,10(1):23-24.
作者姓名:周忠  高兴亚  林艳华
作者单位:贵州省贵阳市肺科医院,贵州,贵阳,550006
摘    要:目的]比较HP及MVP方案对晚期非小细胞肺癌的疗效和毒性.方法]分析HP及MVP化疗方案治疗59例晚期非小细胞肺癌.结果]HP组有效率为50.0%(其中5例复治者中PR3例),MVP组有效率为51.6%,两组间无差异性(P>0.05),毒性反应以骨髓抑制、恶心呕吐及腹泻为主.结论]HP方案是治疗晚期非小细胞肺癌的有效方案.

关 键 词:  非小细胞肺  药物疗法  羟基喜树碱  拓扑异构酶  顺铂
文章编号:1671-170X(2004)01-0023-02
修稿时间:2003年11月21

A Comparsion of HP Regimen and MVP Regimen for Advanced Non-small Cell Lung Cancer
ZHOU Zhong,GAO Xing-ya,LIN Yan-hua.A Comparsion of HP Regimen and MVP Regimen for Advanced Non-small Cell Lung Cancer[J].Journal of Oncology,2004,10(1):23-24.
Authors:ZHOU Zhong  GAO Xing-ya  LIN Yan-hua
Abstract:To compare the efficacy and toxicity of HP regimen(HCPT and DDP)and MVP regimen(MMC,VDS and DDP)in advanced non-small cell lung cancer(NSCLC).The clinical data of59cases with advanced NSCLC treated with HP and MVP were analysed.The response rate was50%in patients with HP group(there were3PR in5previousely treated cases),51.6%in patients with MVP group.There was no significant difference between two groups(P>0.05).The major toxicities in the two groups were leucopenia,nausea and diarrhea.Conclusion]HP regimen is effective for the treatment of advanced NSCLC patients.
Keywords:cancer  non-small cell lung  drug therapy  hydrosylcamptothecin  topoisomerase  cisplatin
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