肝豆状核变性骨密度测定与骨关节症状的研究

目的 探讨肝豆状核变性(HLD)骨密度测定及临床骨关节症状。方法 216例HLD中内脏型63例、脑型102例、脑-内脏型51例，分析各型骨密度值、血钙、24h尿钙及骨关节病变。结果 99例(45.83％)骨密度减低，51例(23．61％)有骨关节症状，20例(9．26％)以骨关节症状首发。结论 HLD可出现继发性骨质疏松症，骨密度测定可较早期地发现骨关节损害，有助于预防和减少骨关节变形和骨折。

A study on bone densitometry testing and osteoarticular symptom in hepatolenticular degeneration

Objective To probe into the bone density and osteoarticular symptom of 216 cases in hepatolenticular degeneration(HLD).Methods 216 cases included 63 splanchnic type cases,102 encephalon type cases,51 encephalon-splanchnic type.And each type bone density,serum calcium,24 hours urine calcium and osteoarticular symptom were analyzed.Results Bone density turned down in 99 cases(45.83%),osteoarticular symptom expressed in 51 cases(23.61%),osteoarticular symptom expressed in 20 cases(9.26%) firstly.Conclusions HLD can appear secondary osteoporosis.Bone densitometry testing can discover the earlier period osteoarticular injures in hepatolenticular degeneration,which militate to prevent and reduce bone joint transform or bone fracture.