| 直肠癌根治术后介入导管动脉化疗对肝转移的预防作用 |
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| 引用本文： | 刘勇敢,李亚伟,陈成立,武现生,许震,代少登,高春芳. 直肠癌根治术后介入导管动脉化疗对肝转移的预防作用[J]. 中国肿瘤临床与康复, 2001, 8(1): 40-41 |
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| 作者姓名： | 刘勇敢 李亚伟 陈成立 武现生 许震 代少登 高春芳 |
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| 作者单位： | 1. 洛阳市中心医院肛肠外科
2. 解放军150中心医院 |
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| 基金项目： | 洛阳市科委重点科研基金资助(99031号) |
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| 摘 要： | 目的探讨介入导管动脉化疗对直肠癌根治术后患者肝转移的作用。方法治疗组56例直肠癌常规根治术后患者，以介入导管动脉化疗替代全身静脉化疗，靶血管为肝固有动脉、肠系膜上动脉、双侧髂内动脉；对照组44例，采用常规静脉化疗；两组化疗方案均为5-Fu+DDP+MMC，治疗后观察其5年的肝转移发生率及存活率。结果治疗组5年内出现肝转移8例(14.3%)。死亡16例，5年存活率71.4%；对照组肝转移9例(20.5%)，死亡17例，5年存活率61.4%，两组的肝转移发生率和5年存活率均有显著差异(P<0.01)。结论直肠癌常规根治术后患者以介入导管动脉化疗替代全身静脉化疗可明显降低肿瘤肝转移的发生率，提高其5年存活率。
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| 关 键 词： | 直肠肿瘤；肝肿瘤/继发性；导管插入术 |
| 文章编号： | 1005-8664(2001)01-40-02 |
| 修稿时间： | 2000-01-10 |
The preventive effect onhepatic metastasis from rectal cancer after redical resection by intraarterial regionalchemotherapy |
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| LIU Yong gan,LI Ya wei,CHEN Cheng li.et al. The preventive effect onhepatic metastasis from rectal cancer after redical resection by intraarterial regionalchemotherapy[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 2001, 8(1): 40-41 |
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| Authors: | LIU Yong gan LI Ya wei CHEN Cheng li.et al |
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| Affiliation: | LIU Yong gan,LI Ya wei,CHEN Cheng li.et al Department of Anorectal Surgery,The Central Hospital of Luoyang,luoyang,471009[ |
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| Abstract: | Objective To evaluate the effect of catheterization of intraarterial chemoterapy on hepatic metastasis from rectal carcinoma after redical resection.Methods Fifty six patients undergoing radical resection for their rectal carcinoma were given intraarterial regional chemotherapy consisting of 5 Fu,MMC and DDP.The rate of hepatic metastasis and 5 year survival rate were observed.Results The rate of hepatic metastasis from rectal carcinoma was 14.3% and 5 year survival rate was 71.4% respectively,while the rate of hepatic metastasis and survival rate for the control group were 20.4% and 61.4%.Conclusions The intraarterial chemotherapy can reduce the rate of hepatic metastasis from rectal carcinoma after redical resection and increase the 5 year survival rate. [ |
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| Keywords: | rectal neoplasms secondary hepatic neoplasms catheterization |
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