Involvement of tumour necrosis factor and other cytokines in immune-mediated vascular pathology |
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| Authors: | G E Grau P F Piguet P Vassalli P H Lambert |
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| Institution: | Department of Pathology, University of Geneva, Switzerland. |
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| Abstract: | Vascular endothelial cells are actively involved in coagulation and inflammation processes and appear to represent an important element in cell-mediated immune responses. In this paper, the possible role of endothelial cells as a target for immunopathological reactions was analyzed. Experimental neurovascular lesions were studied in a model of cerebral malaria, with particular attention to the role of cytokine interactions in vivo. |
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