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Real-Time PCR as a Prognostic Tool for Human Congenital Toxoplasmosis |
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| Authors: | Júlia Gatti Ladeia Costa Ana Carolina Aguiar Vasconcelos Carneiro Alice Thomáz Tavares Gláucia Manzan Queiroz Andrade Daniel Vitor Vasconcelos-Santos José Nélio Januário Daniel Menezes-Souza Ricardo Toshio Fujiwara Ricardo Wagner Almeida Vitor |
| Institution: | Departamento de Parasitologiaa;Departamento de Pediatriab;Núcleo de Ações e Pesquisa em Apoio Diagnósticoc;Departamento de Oftalmologia,d Universidade Federal de Minas Gerais, Belo Horizonte, Brazil |
| Abstract: | Real-time PCR (qPCR) was positive in 72/150 (48%) blood samples of newborns with congenital toxoplasmosis. Among infants with active retinochoroiditis, 68% had positive qPCR results, while positivity was 29% (P = 0.009) in the absence of ocular involvement. Positive qPCR was associated with the presence of retinochoroidal lesions, with an odds ratio of 2.8. |
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