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Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement
Affiliation:1. Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan;2. Department of Cardiology, Chiba Emergency Medical Center, Chiba, Japan;3. Department of Cardiovascular Medicine, International University of Health and Welfare, Narita, Japan;4. Department of Cardiology, Kawasaki Saiwai Hospital, Kawasaki, Japan;5. Department of Cardiovascular Surgery, Kawasaki Saiwai Hospital, Kawasaki, Japan;6. Department of Aortic Surgery, Kawasaki Saiwai Hospital, Kawasaki, Japan;7. Department of Cardiovascular Medicine, Asahi General Hospital, Asahi, Japan;8. Department of Cardiology, Funabashi Municipal Medical Center, Funabashi, Japan;9. Division of Cardiology, Department of Internal Medicine, Iwate Medical University Hospital, Yahaba, Japan;10. Division of Community Medicine, Department of Medical Education, Iwate Medical University Hospital, Yahaba, Japan;11. Division of Cardiology, Chiba Cerebral and Cardiovascular Center, Ichihara, Japan;12. Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan;13. Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan;14. Division of Cardiology, Fukuyama Cardiovascular Hospital, Fukuyama, Japan;15. Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, Kumamato, Japan;p. Division of Cardiology, Saiseikai Kumamoto Hospital, Kumamato, Japan;q. Department of General Internal Medicine 3, Kawasaki Medical School General Medical Center, Okayama, Japan;r. Department of Cardiovascular Medicine, Fukuoka Kieikai Hospital, Fukuoka, Japan;s. Division of Cardiology, Kimitsu Central Hospital, Kisarazu, Japan;t. Department of Cardiology, Tokyo Women''s Medical University Hospital, Tokyo, Japan;u. Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan
Abstract:Subclinical leaflet thrombosis (LT) may occur following surgical and transcatheter aortic valve replacement. Computed tomography (CT) has become an established imaging modality to diagnose subclinical LT following bioprosthetic aortic valve replacement. Even so, there is a limited (but growing) experience in utilizing CT imaging for this indication. This review emphasizes a systematic approach to acquiring and analysing CT imaging for subclinical LT, highlighting evidence surrounding clinical sequelae of subclinical LT and anti-thrombotic implications following diagnosis.
Keywords:Leaflet thrombosis  TAVR  Aortic valve replacement  Computed tomography  Aortic stenosis  4D"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Four-dimensional  CI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Confidence interval  CT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Computed tomography  CVE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Cerebrovascular events  DOAC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Direct oral anticoagulants  HALT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Hypo-attenuated leaflet thickening  LT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Leaflet thrombosis  OAC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Oral anticoagulation  RELM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Reduced leaflet motion  RR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0130"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Relative risk  SAVR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0140"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Surgical aortic valve replacement  TAVR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0150"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Transcatheter aortic valve replacement  VR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0160"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Volume rendering
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