老年人肺癌的诊断与治疗

 肺癌目前是肿瘤中最常见、致死率最高的疾病。据统计，50 %以上的晚期非小细胞肺癌（NSCLC）患者诊断时年龄超过65岁。随着年龄的增长，人体的器官功能、药物的药代动力学都随之改变，故老年肺癌患者在治疗方面有其特殊性，选择方案时必须考虑到其机体生理和病理状态的改变。对老年肺癌目前的诊治进展作一综述

Progress in diagnosis and treatment of lung cancer in the elderly

Lung cancer is the most common cancer and the leading cause of cancer-related deaths in the world. More than 50 % of advanced NSCLC are diagnosed in patients older than age 65 years. Aging is inextricably associated with decreases in marrow reserve, drug clearance, and lean body mass. Elderly cancer patients often present with medical and physiologic challenges that make the selection of their optimal treatment daunting. This article reviews the progress in diagnosis and treatment of lung cancer in the elderly in recent years.